肺鳞30月，父亲永远地走了

滴水 · 发表于 2012-4-10 13:23:38

昨晚开始咳嗽增加，自述身上不舒服，吃了感冒药能好点。不知道是真的感冒，还是特开始耐药了。特才吃了1个半月。

憨豆精神 · 发表于 2012-4-10 16:16:53

滴水发表于 2012-4-10 13:23
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昨晚开始咳嗽增加，自述身上不舒服，吃了感冒药能好点。不知道是真的感冒，还是特开始耐药了。特才吃了1个半 ...

曾经感冒，咳嗽就与癌与靶向药无关而是感冒后后遗症，可以延续很长的时间。

滴水 · 发表于 2012-4-10 20:50:54

憨豆精神发表于 2012-4-10 16:16
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曾经感冒，咳嗽就与癌与靶向药无关而是感冒后后遗症，可以延续很长的时间。

多谢憨叔指点！现在就是不知道如何分辨是感冒，还是特耐药（或者转来的药有问题），还是间质性肺炎。是不是只有医院CT才能确诊。

滴水 · 发表于 2012-4-12 10:29:56

4月11日：医院没有床位，自己买了地塞米松+抗生素。地塞米松4粒(0.75mg/粒)，每6小时一次，效果显现。现在的问题是放射性肺炎复发还是特罗凯引起的间质性肺炎如何区分？
止咳用了咳快好，比右美沙芬效果好。

滴水 · 发表于 2012-4-13 08:32:29

4月13日：现在情况好了很多，说明激素起作用了。特也暂停了，止咳药很管用，咳嗽控制住了。
现在的问题是，一天到晚打嗝，影响休息，不知道有没有啥办法。

滴水 · 发表于 2012-4-15 17:25:14

本帖最后由滴水于 2012-4-15 18:20 编辑

用了蓝天推荐的胶体果胶铋胶囊，打嗝真的好了，特来报告下，给其他人参考。

另外，我查到打嗝可能是地塞米松引起的。

滴水 · 发表于 2012-4-15 20:10:48

最近排便经常腹痛（时好时坏，不知道啥原因）。

滴水 · 发表于 2012-4-15 20:32:40

本帖最后由滴水于 2012-4-16 21:21 编辑

现在我猜我老爸是放射召回性肺炎
Radiation recall pneumonitis (RRP) occurs in a previously irradiated field and is triggered by certain cytotoxic drugs, principally chemotherapeutic agents such as erlotinib.
Erlotinib is a reversible epidermal growth factor receptor tyrosine kinase inhibitor (TKI) and is an effective second-line treatment for patients with advanced-stage non-squamous-cell lung cancer. Previously, only 2 cases of radiation recall after erlotinib treatment have been reported. Here, we report a case of RRP caused by treatment with erlotinib 4 months after palliative definitive hypofractionated radiation therapy (RT). Patient and Methods: A 58-year-old male patient with non-small cell lung cancer (adenocarcinoma) was treated with polychemotherapy, palliative RT (30 Gy in 10 fractions), and erlotinib thereafter. Results: Dosimetric analysis obtained from a 3-dimensional conformal RT planning system revealed that the volume of lung receiving at least 20 Gy (V20) was 21.2% and the mean lung dose was 12.7 Gy. These data indicate that systemic administration of a TKI, even after palliative RT, may lead to unexpected toxicity when the radiation field encompasses visceral organs. Conclusion: We conclude that the use of a TKI after RT may trigger radiation pneumonitis. Although evidence is limited, we advise clinicians to be cautious of RRP after erlotinib treatment.